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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STON2
All Species:
8.79
Human Site:
S249
Identified Species:
17.58
UniProt:
Q8WXE9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WXE9
NP_149095.2
905
101165
S249
C
P
L
P
P
V
T
S
P
L
K
P
N
T
P
Chimpanzee
Pan troglodytes
XP_001135210
905
101144
S249
C
P
L
P
P
V
T
S
P
L
K
P
N
T
P
Rhesus Macaque
Macaca mulatta
XP_001105584
896
100013
S249
C
P
L
A
P
I
T
S
P
L
K
P
N
T
P
Dog
Lupus familis
XP_864856
735
82747
L124
S
G
G
G
S
S
L
L
P
T
K
S
T
C
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZ60
895
99593
K249
S
P
P
V
P
S
P
K
K
P
N
T
P
S
A
Rat
Rattus norvegicus
NP_001129346
895
99472
K249
S
P
T
V
P
S
P
K
K
P
N
A
P
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505629
865
95494
K249
P
P
S
T
S
P
S
K
S
D
S
P
S
R
P
Chicken
Gallus gallus
XP_421302
887
99388
Q249
D
T
S
A
L
E
T
Q
A
P
D
V
N
F
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001028915
859
96510
N248
N
S
I
F
A
F
D
N
T
L
S
K
N
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24212
1262
137751
L278
A
A
P
E
A
D
D
L
L
D
M
F
G
T
T
Honey Bee
Apis mellifera
XP_396872
1188
129859
E419
D
L
L
G
D
F
G
E
P
I
T
T
D
T
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795059
1041
114812
V303
E
V
S
R
F
S
E
V
A
T
G
P
E
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.9
31.4
N.A.
86.1
85.8
N.A.
68
69.8
N.A.
48.5
N.A.
23.6
24.7
N.A.
25.5
Protein Similarity:
100
99.6
98
49.5
N.A.
90
89.7
N.A.
76.8
79.8
N.A.
61.7
N.A.
38.7
40
N.A.
44.6
P-Site Identity:
100
100
86.6
13.3
N.A.
13.3
13.3
N.A.
20
13.3
N.A.
13.3
N.A.
6.6
20
N.A.
13.3
P-Site Similarity:
100
100
93.3
13.3
N.A.
20
20
N.A.
33.3
13.3
N.A.
33.3
N.A.
6.6
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
17
17
0
0
0
17
0
0
9
0
0
25
% A
% Cys:
25
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
17
0
0
0
9
9
17
0
0
17
9
0
9
0
0
% D
% Glu:
9
0
0
9
0
9
9
9
0
0
0
0
9
0
0
% E
% Phe:
0
0
0
9
9
17
0
0
0
0
0
9
0
9
0
% F
% Gly:
0
9
9
17
0
0
9
0
0
0
9
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
9
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
25
17
0
34
9
0
0
0
% K
% Leu:
0
9
34
0
9
0
9
17
9
34
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
9
0
0
17
0
42
0
17
% N
% Pro:
9
50
17
17
42
9
17
0
42
25
0
42
17
0
34
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% R
% Ser:
25
9
25
0
17
34
9
25
9
0
17
9
9
25
0
% S
% Thr:
0
9
9
9
0
0
34
0
9
17
9
17
9
50
9
% T
% Val:
0
9
0
17
0
17
0
9
0
0
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _